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Full Encryption Digital Signatures Data-Image Support Cross-Platform format* Buffers, DNA, RNA, Protein tools
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DOWNLOAD
version 4.0.5 j - a single,
customizable paperless lab solution Email for questions and requests |
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main features positive user experience from a fast locally executed C++ code; also: |
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Non-proprietary HTML format of ELN for instant sharing across platforms* Date-Time-ID-based organization of pages with open-ended hyperlinking Search within records that accepts regular expressions synthax Optional OTF encryption of projects: TrueCrypt integration as of version 4.0.2 Support of data, images and hand drawings integration into pages Lab Modules** for solution making, DNA and protein sequence analysis and design Use of digital signatures to prove that records existed at a certain point in time Automatic audit and reporting from researcher's notebook to a project supervisor Runs in Windows XP to 7, 32-bit & 64-bit, under .NET 3.5; MacOS & Linux via VirtualBox Local installable - no services to subscribe to or extra hardware are required |
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* ELN records can be viewed
in Windows,
MacOS or Linux with any HTML browser.
That way BiochemLabSolutions gives the user full ownership of the data. Even if the program is uninstalled or is not in reach, the records remain fully accessible. One's records can be shared with collaborators running any OS without asking them to have this program installed. ** Modules Versatile calculator of buffers and solutions that can handle both individual and cross-containing components. Compute most complex multi-component mixtures in real time and print mixing sheets directly from the program Database of molecular weights and pKa of common reagents Ionic strength converter, serial solution mixer Calculator of extinction coefficients and concentrations of DNA, RNA and proteins from their sequence; calculator of isoelectric points of proteins DNA sequence into protein translator Unique interactive PCR mutagenesis designer that understands double-clicking of amino acids in a protein sequence to generate optimized PCR primers for mutations or deletions Rare codon finder Built-in finder of least disruptive amino acid mutations and best-pairing amino acids Interactive restriction site finder   
Download an example notebook here (can be viewed directly in most web browsers) This example was also prepared in BiochemLabSolutions 4.0.5, no other HTML editor was used. Biochemistry Lab Solutions is a stand-alone Windows executable. It does not use centralized server, does not require training and elaborate setting up, and is completely ready after installation. The built-in auto reporting module can digitally sign the projects with chosen periodicity. This ensures absolute record integrity and ability to prove that a particular record existed at a specific point in time and has not been altered afterwards. The program can be set to report to a project supervisor or to a principal investigator each time a project snapshot and a digital signature are created on a researcher's computer. See the BLS manual online Record security level..................................................UP TO TOP SECRET (read more) Record creation date can be legally proven..............TRUE F.A.Q. Can one trust electronic records as much as paper? Absolutely if proper measures are taken. This ELN does take these measures by backing up and digitally signing the records periodically. SHA512 algorithm is used for generating the digital signatures. After the backup is digitally signed, it is impossible to modify anything in its files (not even add one comma) without completely breaking the signature. This makes electronic records no less trustworthy than traditional paper records. SHA512 has no publically known weaknesses and can't be "broken in" under any scenarios. This procedure is carried out automatically and does not require user actions (except to initially configure the Auto Audit module). SHA512 keys can be automatically Emailed to any number of recepients at time of signing the project. Example of SHA512 electronic signature for a project with 20 pages: rTy6iJJYogOufVaBJ7028sJbw2jPATiqnyuypbCKmglmCj+PWfET itoKoIz7Fm6KR8Yzpy38uWM52Kl2hfMhDA== After a single space character was erased from one of the pages: 25XEbx2tsPnoHov09JGT5Lfz8BFYTqICMBM1UC1frbf31EqyNyqv zAz+Ul2QRqWYAVz9A1No7NWCFIPx3g6KdA== The user-edited project key no longer matches the original date-time stamped key. 21 CFR part 11 compliance of the electronic record keeping 21 CFR part 11 sets a specific set of requirements to ensure legal integrity of the electronic records. BiochemLabSolutions digital signature module can be set up to automatically sign the projects and includes the following: Manifestations to contain information associated with the signing of electronic records. This information must include the printed name of the signer, the date and time when the signature was executed, and the meaning (such as review, approval, responsibility, and authorship) associated with the signature. In addition, this information is subject to the same controls as for electronic records and must be included in any human readable forms of the electronic record (such as electronic display or printout). Under Sec. 11.70, electronic signatures and handwritten signatures executed to electronic records must be linked to their respective records so that signatures cannot be excised, copied, or otherwise transferred to falsify an electronic record by ordinary means. Under the general requirements for electronic signatures, at Sec. 11.100, each electronic signature must be unique to one individual and must not be reused by, or reassigned to, anyone else. Note, it is responsibility of the end users, not of BiochemLabSolutions.com, to use the applications in a compliant configuration. BiochemLabSolutions.com only provides the means to do trusted record keeping but does not control the use of the program. Note that when configured properly, the approach used by the BiochemLabSolutions effectively eliminates the factor of Personnel Integrity. Even if the records are stored in a freely editable form on a researcher's computer, the distributed key will only match 100% authentic records. The scope of automatic key distribution can include a virtually unlimited number of parties (witnesses) who can challenge and verify or refute authenticity of the records in question using their own electronic key they receive by e-mail. Why the program doesn't run and gives a cryptic error message? Almost certainly because your computer does not have .NET 3.5 installed. Please install the .NET framework 3.5. It is a necessary Microsoft library required for this program to run. .NET 3.5 might not be in your OS by default. See link above. The program crashes in Vista / Windows 7 The program requires Administrative privileges to run. Simply logging in as Administrator may not be enough. To overcome the problem, either disable Windows UAC altogether or launch the program with administrative privileges by right-mouse clicking its icon and selecting "Run as administrator". Obtaining the license If you tested and liked the program, use the built-in licensing tool or ask for a price quote at: eln 
biochemlabsolutions.comThe program will work free without the license but with some limitations. Download Supported OS: Windows XP, Vista 32/64 bit, Windows Server 2003 and 2008, Windows 7. .NET 3.5 must be installed for the program to run. Otherwise, an error code will appear. A note about UAC of Windows: you may see an error message when starting the program if your UAC is turned on because Administrative priviliges are required to run. Solution 1 (preferred): find C:\Program Files\Biochem Lab Solutions ....\Biochem Lab Solutions.exe, right-click the exe file find Compatibility->Privilege Level check "Run this program as Administrator", done Solution 2 Right-click program icon, select "Run as administrator" Solution 3 (only for advanced users, do at your own risk) Disable Windows UAC MacOS and Linux users can run this program at native speed via free VirtualBox by Sun Microsystems. New in the most recent versions: - Audit module was improved to allow very rapid daily backup & audit - Overall workflow improvements - New zoom function to adjust both, visible and printable size of ELN pages - Compatibility with Internet Explorer v. 6, 7 and 8, and with Mozilla Firefox was enhanced - Tool to find least-disruptive mutations added to the protein mutagenesis module - Hyperlink edit/insert was added to the page editor - Overall reliability has been improved - Integrated TrueCrypt support added. This feature introduces the most trusted open source on-the-fly encryption capability to BiochemLabSolutions. Even the largest notebooks can be accessed and worked with instantly, while maintaining cutting edge security of all records granted by TrueCrypt. BiochemLabSolutions.com © 2007-2009 |
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