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Comments from users
"I used the program and I liked it very much. Thanks for making such a nice application. It made our work very easy."
"I need this software for my students, thank you"
"I love this software. It made my research easier and it helped me a lot in solutions preparation."
"Thats good"
"Like this programm..."
"Great app!!"
...
BiochemLabSolutions main features
Non-proprietary HTML format of all records for easy sharing across platforms*
Hierarchical automatic organization of pages
Quick keyword search within records (accepts regular expressions synthax)
Option for encryption of projects: TrueCrypt integration as of version 4.0.2
Ability to incorporate files, images and hand-drawn sketches
LabTools Modules** for solution making, DNA and protein sequence analysis and design
Trustworthy record keeping to prove that records existed at a certain point in time
Automatic reporting from researcher's notebook to a project supervisor
Runs in Windows 2003, XP and Vista 32-bit & 64-bit under .NET 3.5
Zero maintenance cost - no services to subscribe to are necessary
* There is no need to install the program to open, read or edit the electronic records - they can be opened on Windows, MacOS or Linux computers using any HTML browser. That way BiochemLabSolutions gives the user full ownership of the data. Even if the program is uninstalled or is not in reach, all the records remain fully accessible.
** Modules
Versatile calculator of buffers and solutions that can handle both individual and cross-containing components
In use, it is a powerful solutions calculator, dilution calculator and buffer calculator that computes
even highly complex multi-component mixtures in real time and can output handy mixing sheets
directly to your printer
Database of molecular weights and pKa of common reagents
Ionic strength converter, serial solution mixer
Calculator of extinction coefficients and concentrations of DNA, RNA and proteins from their sequence;
calculator of isoelectric points of proteins
DNA sequence into protein translator
Unique real-time PCR mutagenesis designer that understands double-clicking of amino acids in a
protein sequence to generate optimized PCR primers for mutations or deletions
Comprehensive and fast real-time restriction site finder
Download an example notebook here (can be viewed directly in most web browsers)
This example was also prepared in BiochemLabSolutions 4.0.5, no other HTML editor was
used.
Biochemistry Lab Solutions is a stand-alone Windows executable. It does not use centralized server, does not require training and elaborate setting up, and is completely ready after installation. The built-in auto reporting module can digitally sign (lock) the content of the projects periodically. This ensures absolute record integrity and ability to prove that a particular record existed at a specific point in time and has not been altered afterward. The program can be set to report to the project supervisor or to the principal investigator each time a project snapshot and a digital signature are created on a researcher's computer.
See the BLS manual online
Who may use BLS?
Researchers of any level who would like or need to keep
organized, searchable and secure electronic records.
The word "Biochemistry" is used in the title to reflect the presence of
built-in modules commonly used in a biochemistry lab.
But the record keeping module of BLS (ELN) is completely independent and
can be used as a secure electronic notebook by anyone.
F.A.Q.
Can the digital protection of record authenticity be compromised?
SHA512 algorithm is used for generating digital signature.
After the projects are digitally signed, it is impossible to modify anything in
their files and not break the signature. This makes electronic records no less
trustworthy than traditional paper records.
21 CFR part 11 compliance of the electronic record keeping
21 CFR part 11 sets a specific set of requirements to ensure legal integrity of
the electronic records. BiochemLabSolutions digital signature module can be
set up to automatically sign the projects and includes all of the following:
...section 11.50 requires signature
manifestations to contain information associated with the signing of
electronic records. This information must include the printed name
of the signer, the date and time when the signature was executed,
and the meaning (such as review, approval, responsibility, and
authorship) associated with the signature. In addition, this information
is subject to the same controls as for electronic records and must be
included in any human readable forms of the electronic record (such
as electronic display or printout).
Under Sec. 11.70, electronic signatures and handwritten signatures
executed to electronic records must be linked to their respective
records so that signatures cannot be excised, copied, or otherwise
transferred to falsify an electronic record by ordinary means. Under
the general requirements for electronic signatures, at Sec. 11.100,
each electronic signature must be unique to one individual and must
not be reused by, or reassigned to, anyone else.
Note, it is responsibility of the end users, not of BiochemLabSolutions.com,
to use the applications in a compliant configuration. BiochemLabSolutions.com
only provides the means to do trusted record keeping but does not control
the use of the program.
Note that when configured properly, the approach used by the
BiochemLabSolutions effectively eliminates
the factor of Personnel Integrity. Even if the records are stored in a freely
editable form on a researcher's computer, the distributed key will only match
100% authentic records. The scope of automatic key distribution can include
a virtually unlimited number of parties (witnesses) who can challenge
and verify or refute authenticity of the records in question using their own
electronic key they receive by e-mail.
The program wouldn't run at all, giving a cryptic error message. Why?
Almost certainly because your computer does not have .NET 3.5 installed.
Please install the .NET framework 3.5. It is a necessary Microsoft library required
for this program to run. .NET 3.5 might not be in your OS by default. See link above.
The program crashes in Vista / Windows 7
The program requires Administrative privileges to run. Simply logging in as
Administrator may not be enough. To overcome the problem, either disable
Windows UAC altogether or launch the program with administrative privileges
by right-mouse clicking its icon and selecting "Run as administrator"
Obtaining the license
If you tested and liked the program, use the built-in licensing tool or
ask for a price quote at
eln
biochemlabsolutions.comThe program will work free without the license but will have certain limitations.
Download a fully functional, non expiring version 4.0.5 here.
Supported OS: Windows XP, Vista 32/64 bit, Windows Server 2003 and 2008, Windows 7
.NET 3.5 must be installed for the program to run. Otherwise, an error code will appear.
MacOS and Linux users can run the program via free VirtualBox by Sun Microsystems
New in the most recent versions:
- Overall workflow improvements
- New zoom function to adjust both, visible and printable size of ELN pages
- Compatibility with Internet Explorer v. 6, 7 and 8, and with Mozilla Firefox was enhanced
- Tool to find least-disruptive mutations added to the protein mutagenesis module
- Hyperlink edit/insert was added to the page editor
- Overall reliability has been improved
- Integrated TrueCrypt support added. This feature introduces the most trusted open source
on-the-fly encryption capability to BiochemLabSolutions. Even the largest notebooks can be
accessed and worked with instantly, while maintaining cutting edge security of all records
granted by TrueCrypt.
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